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What are the relationship between environmental effector and sickle cell patient

A Draft literature review about sickle cell anemia 
(the research problem is sickle cell disease ) and
 the question of research (what are the relationship between environmental effector and sickle cell patient),
  
Description of Assignment: 
You are to locate research articles on your pre-approved topic. You are to write not less than 15 pages summary the general theme(s) of these articles as it pertains to your topic. A reference sheet, listing the articles should also be included (this does not count toward your page limit). This summary should serve as the background/foundation for your survey instrument.  

     
ASSIGNMENT BASICS
 
Articles ,
Theme, Background/Foundation , Research Question, Reference Sheet