BIOL1051H Web WI2021 Case Study 2 ENDOCRINE SYSTEM (7%)
16 MARKS TOTAL DUE FRIDAY MARCH 19, 2021
Based on this case study and other information in this chapter, answer the following questions. References are not required. However, if you use resources outside those provided to you, make sure to reference them. Do not answer using quotations answers should be in your own words!
1. Explain what the effect of prednisone would be on the secretion of hormones in the
Hypothalamic-Pituitary-Adrenal Axis (4 marks)?
2. Use of the drug prednisone led to signs that imitate those of an endocrine disease. a. What endocrine disease does it mimic (1 mark)? b. Briefly describe the hormonal imbalance that leads to this disease (2 marks). c. Why does prednisone mimic this disease (1 mark)?
3. Use what you know about regulation of endocrine function to explain why the ACTH level is elevated in Addison disease (3 marks)? 4. Individuals with excess secretion of growth hormone may develop diabetes mellitus as a side effect. Would you expect this diabetes to be type I or type II (1 mark)? Explain your reasoning (1 mark). 5. A test of thyroid function that can be done to test for hyperthyroidism is to measure uptake of radioactive iodine into the thyroid gland. Explain the reason that radioactive iodine is indicative of thyroid function (3 marks).
